Laboratory Testing for Lupus Anticoagulants

Laboratory testing for lupus anticoagulants (LA) is performed by clinical laboratories to evaluate patients with vascular thrombotic events, recurrent spontaneous miscarriages, and/or suspected antiphospholipid syndrome (APS). Furthermore, patients demonstrating unexplained, prolonged activated partial thromboplastin time (APTT) may also undergo LA testing.

This interactive training tool is designed to share best practices on how to perform and interpret LA tests according to published guidelines* and thereby aid in better patient management.

*Ledford-Kraemer MR, Moore GW, Bottenus R, Daniele C, de Groot PG, Exner T, Favaloro EJ, Moffat KA, Nichols WL. Laboratory Testing for the Lupus Anticoagulant. Approved Guideline – First Edition. CLSI document H60. Wayne, PA: Clinical and Laboratory Standards Institute; 2014.